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Senior Technical Specialist, Metabolite Identification (3252927581)

Technology 信息技術

Technical Specialist


GCSE/Scottish Standard Grades A-Level Postgraduate or above 碩士或以上 Undergraduate or above 學士或以上 Intermediate apprenticeship 學徒

PSW Apprenticeship 學徒 華語工作 Contract 合同制 Full-Time 全職 Internship 實習 Part-Time 兼職


Northamptonshire, Northamptonshire, United Kingdom

We offer: Vibrant and dynamic employment – we are a highly specialised, growth company operating in a critical sector of the economy – our future is strong and exciting Opportunities to develop your skills and yourself – our rapid growth brings greater opportunities for you to learn and grow faster A great team where we all support each other – enjoy your work – after all you spend about a third of your time here Our Company: “We are a dynamic, fast-growing company, with an enviable reputation for leading edge science, offering contract research services to some of the world’s leading pharmaceutical companies, solving what were believed to be unsolvable scientific challenges”. We believe in our ability to relentlessly push forward the boundaries of scientific excellence, delivering solutions for our clients, always operating ethically and with integrity. We take pride in our professionalism and commitment to always deliver our very best work. The role is based in Northamptonshire, in the town of Rushden. The Rushden site is a centre of excellence for Radiolabelled Sciences incorporating both Metabolism (which includes Clinical Metabolism, Pre-clinical ADME, In vitro and DDI services, Large Molecule Metabolism, Environmental Fate, Plant Metabolism and Metabolite Identification) in addition to Chemistry (which includes API and IMP manufacture). We offer our employees a supportive teamwork environment, enabling them to develop and liberate their true potential. The position we are seeking to fill is for a Senior Technical Specialist, Metabolite Identification to bring their expertise in High Resolution Mass Spectrometry to identify metabolites generated in studies for new product development. -We offer state of the art equipment and facilities at our Rushden site. -We offer a competitive salary and a progressive and comprehensive suite of employee benefits. -We offer the opportunity for growth and development. Responsibilities: The successful candidate will have responsibilities for: -Bringing expertise in structure elucidation. -Conducting analytical and metabolite identification work for both regulatory and non-regulatory In Vitro, In Vivo, Clinical, Large Molecule (Biological) and Environmental-Fate studies to successfully fulfil all the requirements of a study to the timelines stated in the Study Plan/Analytical Work Plan, under direction of the Study Director or Analytical Project Manager. -Being responsible for the development of LC-MS/MS chromatographic methods within the group and act as an expert consultant on the development of chromatographic methods within the wider Metabolism Department. -Developing technical training materials and maintaining of laboratory work standards. -Mentoring of new Technical Specialists and other senior laboratory staff in their area. -Providing technical advice to Study Directors/Management at all points in the study life cycle. -Holding equipment/software/lab space responsibilities on behalf of their team. -Actively contributing to client visits and teleconference as appropriate. -Responsible for conducting of the appropriate experimental work required to successfully fulfil all the requirements of a study to the timelines stated in the Study Plan, under direction of the Study Director. -Work with Study Director on client communication, contributing scientifically to client discussions, as appropriate. -Initiating and maintaining an active role in the implementation of new service-level procedures as required, enhancing the service offerings of Pharmaron. -Interpreting the relevant data and prepare accurate scientific study updates and study report sections. -Leading implementation of continuous improvement culture in specialist area proposing process improvement/new service offering initiatives to the Metabolism leadership team. -Keep up to date with technical developments in specialist area recommending new techniques and working with management to compile justification for Capex projects. Qualification -PhD, MSc or BSc (Hons) in Chemistry, Biochemistry or related subject Requirements: -Experience in metabolite identification in a CRO or Pharmaceutical/Agrochemical company. -Experience in chromatographic method development -Experience of working in a GLP facility -Expert in use of High Resolution Mass Spectrometers e.g. Waters Vion, Thermo QExactive -Expert in use of relevant software e.g. Xcalibur, Waters UNIFY, Compound Discoverer -Knowledge of metabolism/metabolic reactions -LC-MS/MS data interpretation skills -Coaching & Mentoring -Project Management -Scientific data interpretation, reporting and presentation skills -Effective written and verbal communication skills, including the ability to effectively present scientific findings to colleagues and clients Why Should You Apply? -This is an opportunity for you as a Technical expert in High Resolution Mass Spectrometry to demonstrate your ability to make a real impact in a highly scientific and regulated environment -Build and shape your career in an environment that sets and commits to the highest standards of scientific research. -To be part of a team who support each other, embrace and solve technical challenges and put excellence at the heart of all that we do. Pharmaron is a premier R&D service company supporting the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities having established diverse drug R&D service capabilities, ranging from synthetic, medicinal and analytical chemistry, biology, DMPK, pharmacology, drug safety assessment, radiochemistry and isotopically labelled metabolism, chemical & pharmaceutical development to clinical development. With operations in China, US and UK staffed by over 15,000 employees, Pharmaron has an excellent track record in the delivery of R&D solutions to its partners in North America, Europe, Japan and China